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Provedor de dados:  J. Venom. Anim. Toxins incl. Trop. Dis.
País:  Brazil
Título:  Anti-inflammatory activity of the apolar extract from the seaweed Galaxaura marginata (Rhodophyta, Nemaliales)
Autores:  Rozas,E.
Freitas,J. C.
Data:  2007-01-01
Ano:  2007
Palavras-chave:  Seaweed
Galaxaura marginata
Inflammation
Croton oil
Edema
Anti-inflammatory agents
Resumo:  The red seaweed Galaxaura marginata (Ellis & Solander) Lamouroux, well known by the antibacterial activity of its polar extract and the cytotoxic activity of its oxygenated desmosterol, showed anti-inflammatory action in its apolar fraction. Topical anti-inflammatory activity was observed in samples collected at São Sebastião channel, northern littoral of São Paulo State, Brazil. The apolar extract and its fractions obtained through Thin-Layer Chromatography (TLC) reduced the topical inflammation produced by croton oil in mouse ear. Such data indicated that the apolar extract from the marine red alga G. marginata displayed anti-inflammatory activity (since 1mg/ear extract reduced 95±0.5% inflammation), which could be the result of the synergic activity of the four fractions present in the apolar extract.
Tipo:  Info:eu-repo/semantics/other
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000200011
Editor:  Centro de Estudos de Venenos e Animais Peçonhentos
Relação:  10.1590/S1678-91992007000200011
Formato:  text/html
Fonte:  Journal of Venomous Animals and Toxins including Tropical Diseases v.13 n.2 2007
Direitos:  info:eu-repo/semantics/openAccess
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